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The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects

Warnings Do not use in pregnancy, breastfeeding and in children, or in any case for prolonged periods, without consulting the doctor.

10.1016/j.mayocp.2018.09.013 42 SpalingerM

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Acharya, P., Acharya, C., Thongprayoon, C., Hansrivijit, P., Kanduri, S